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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Manage Clinical Trials Data | 5% | - Clean, merge, and subset data - Use SQL and dictionary tables - Access and explore clinical datasets |
| Topic 2: Clinical Trials Process | 5% | - Clinical trial lifecycle and protocol - Derive programming requirements from protocol and CRF |
| Topic 3: Transform or Summarize Clinical Trials Data | 15% | - Aggregation and transposition - Derive variables and study days - Data step manipulation |
| Topic 4: Validate Clinical Trial Data Reporting | 20% | - Use PROC COMPARE and log review - Validation principles - Programming validation techniques |
| Topic 5: Regulatory Submissions | 5% | - Compliance for clinical data reporting - ICH and FDA guidelines |
| Topic 6: Macro Programming for Clinical Trials | 15% | - Debugging macros - Create and call macros - Macro variables and parameters |
| Topic 7: Clinical Trials Data Structures | 10% | - Define.xml and dataset specifications - Clinical domain structures - CDISC standards: SDTM, ADaM |
| Topic 8: Report Clinical Trials Results | 10% | - PROC REPORT and PROC PRINT - Produce tables, listings, and figures |
| Topic 9: Apply Statistical Procedures for Clinical Trials | 15% | - Basic statistical analysis for clinical data - PROC MEANS, FREQ, TABULATE |
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
Given the SAS data set WORK.VS1:
Which value will be assigned to variable TOTAL?
- A. 112
- B. missing
- C. 140
- D. 560
Correct Answer: C 🗳️
This question will ask you to provide lines of missing code.
Which ODS statements, inserted respectively in the two locations indicated above, create a report stored in a PDF file?
- A. ods file pdf='AE.pdf';
ods file close; - B. ods file open='AE.pdf' type=pdf;
ods file close; - C. ods pdf open='AE.pdf';
ods pdf close; - D. ods pdf file='AE.pdf';
ods pdf close;
Correct Answer: D 🗳️
Which statement correctly creates a SAS date variable from a character variable?
- A. sasdate = input(chardate,date9.);
- B. sasdate = put(chardate,date9.);
- C. sasdate = 'chardate'd;
- D. sasdate = date(chardate,date9.);
Correct Answer: A 🗳️
Which code segment would you use to derive the numeric variable AVAL from AVALC by stripping off non-numeric characters?
- A. aval = put(compress(avalc, '<>='), best12.);
- B. aval = input(substr(avalc, 2,2), best12.);
- C. aval = input(compress(avalc, '<>='), best12.);
- D. aval = put(substr(avalc, 2,2), best12.);
Correct Answer: C 🗳️
Study day is defined as DCMDATE minus RFSTDTC +1
Which statement will compute the study day correctly without producing notes for missing values in the log?
- A. STUDYDAY=input(DCMDATE,yymmdd8.)-input(RFSTDTC,date9.)+1;
- B. STUDYDAY=DCMDATE-RFSTDTC+1;
- C. If RFSTDTC^='' and length(DCMDATE)=8 then STUDYDAY=input(DCMDATE,date9.)- input(RFSTDTC,yymmdd8.)+1;
- D. If RFSTDTC^='' and length(DCMDATE)=8 then STUDYDAY=input(DCMDATE,yymmdd8.)- input(RFSTDTC,date9.)+1;
Correct Answer: D 🗳️
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